考虑改进螺线管线圈和自适应模糊控制的磁热疗装置研究
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1.福州大学物理与信息工程学院福州350108; 2.福州大学电气工程与自动化学院福州350108; 3.圣卡塔琳娜联邦大学自动化与系统系弗洛里亚诺波利斯88040-900

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TH702

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国家自然科学基金(62471144)、国家自然科学基金(62071124)项目资助


Research on magnetic hyperthermia device considering improved solenoid coil and adaptive fuzzy control
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1.College of Physics and Information Engineering, Fuzhou University,Fuzhou 350108, China; 2.College of Electrical Engineering and Automation, Fuzhou University,Fuzhou 350108, China; 3.Departamento de Automao e Sistemas, Universidade Federal de Santa Catarina, Florianpolis 88040-900, Brazil

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    摘要:

    针对传统肿瘤磁热疗装置中存在的开关损耗大、反馈系统迟滞且控制效果差、磁场不均匀导致热疗效果差等问题,提出并设计了一种改进磁热疗装置方案。首先,在电路设计方面,通过采用图腾柱驱动电路以解决开关损耗大、驱动能力有限的问题。此外,所提出的控制系统通过光纤测温传感器结合自适应模糊控制PID算法进行功率控制,可保证在不受磁场干扰情况下提高响应速度;通过实时辨识系统动态特性并动态调整控制参数,克服了传统PID控制在非线性、时变系统中反馈滞后且超调大等缺陷。最后,针对磁场不均匀问题亦做了进一步研究,基于有限元建模方法在主体螺线管线圈两侧设计辅助线圈并改进主线圈的尺寸与匝数,从而提升装置的磁场均匀性。实验结果表明,本研究开发的磁热疗装置驱动能力与闭环反馈控制稳定性较原型装置得到显著提高,装置在120~300 kHz的工作频率下磁场均匀性相对偏差δB由改进前的51%降至改进后的1.3%,边缘治疗区域内的稳态温度波动相比改进前提升了约2℃。本系统通过驱动电路与自适应模糊控制PID算法的结合,在改进后的螺线管线圈磁场中能够实现相比现有文献装置更高效的磁-热转换,达到了更快更稳定的升温效应,为磁纳米热疗装置的临床应用提供了更高效的硬件方案。

    Abstract:

    This article proposes and designs an improved magnetic hyperthermia device to address the problem of large switch losses, the feedback system hysteresis and poor control effect, and also the uneven magnetic field leading to poor treatment effect in traditional tumor magnetic hyperthermia device. Firstly, it addresses the issues of high switching losses and limited driving capabilities by using totem pole drive circuits in terms of circuit design. In addition, the proposed control system achieves the power control by the fiber optic temperature sensor combined with an adaptive fuzzy control PID algorithm, which improves the response speed without interference from magnetic field. The proposed strategy also overcomes the feedback lag and large overshoot in nonlinear and time-varying systems for traditional PID control by identifying the dynamic characteristics of the system in real time and dynamically adjusting control parameters. Finally, this article also conducts further research on the problem of uneven magnetic fields based on finite element modeling method, which is improved by designing the auxiliary coils both sides of main solenoid coil and adjusting the size and number of main coil turns. The experimental results show that the proposed magnetic hyperthermia device exhibits significantly enhanced driving capability and closed-loop feedback stability compared to the prototype device. The relative deviation of magnetic field uniformity (δB) is reduced from 5.1% to 1.3% over an operating frequency range of 120~300 kHz. In addition, the steady-state temperature fluctuation within the edge area has increased by approximately 2℃ compared to the original case. Furthermore, this proposed system achieves more efficient magnetocaloric conversion in the improved solenoid coil magnetic field compared to existing devices in the literature after combining the driving circuit with the adaptive fuzzy control PID algorithm. This faster and more stable heating performance provides a more efficient hardware solution for the clinical application of magnetic therapy device.

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汤云东,张颖昊,金涛,Rodolfo C. C. Flesch.考虑改进螺线管线圈和自适应模糊控制的磁热疗装置研究[J].仪器仪表学报,2026,47(1):37-46

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  • 在线发布日期: 2026-03-30
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