Aiming at the non-stationary characteristics of the wireless transmission scene of vehicle-to-vehicle (V2V) communication system and the non-independent characteristics of elevation angles (EAs) and azimuth angles (AAs) in the three-dimensional( 3D) wireless transmission, a novel 3D regular-shaped geometry-based stochastic reference model and the corresponding simulation model for vehicle-to-vehicle (V2V) channels were proposed. In order to describe the non-stationary of the channel, the multiple-time-varying parameters caused by the transceiver vehicle moving in any direction and speed have been added in the proposed model. Some of the statistical characteristics of the model are derived for the case that the EAs and AAs Angle spectrum obey the joint distribution of von mises fisher ( VMF), and the effects of vehicle driving environment, non-stationarities and the driving state at the receiving and transmitting terminals on the space-time correlation function of the channel are investigated in depth. Simulation results show that the proposed channel model can capture the influence of vehicle driving direction changes on the space-time correlation of the channel, the theoretical value of Doppler power spectral density ( DPSD) is basically consistent with the measured value, and the statistical characteristics of the simulation model and the reference model are highly fitted, it demonstrates not only the utility of simulation models but also the correctness of the theoretical derivations and simulations.