To solve the decorrelation phenomenon of digital image correlation when measures large inter-frame deformation, a DIC full-field measurement method based on bilateral feature matching is proposed. Firstly, the ORB (Oriented FAST and Rotated BRIEF) algorithm is used to extract and match the feature point pairs to ensure that a large number of matching point pairs can be quickly extracted. Secondly, to deal with the problem of false matching, a bilateral feature matching is proposed based on the grid-based motion statistics method to eliminate false matching point pairs. Finally, the deformation parameters of each point of interest are independently estimated and provided to the inverse compositional Gauss-Newton algorithm to iteratively obtain the final deformation results. The robustness and accuracy of the proposed method are verified by simulation and large compression tests on the polymer foam. Results demonstrate that the real deformation can be measured by this method is about 40%., which is suitable for measuring large inter-frame compression deformation, and shows great potential in measuring other large inter-frame deformation.