The control of vibration amplitude of flow tube is very essential for Coriolis mass flowmeter (CMF) in the application of measurement. When the singlephase flow and gasliquid twophase flow switch to each other frequently, the current control method would lead to a large attenuation and overshoot of vibration amplitude. Therefore, the experimental scheme is designed and conducted. The reason of the problem is analyzed, and then the variable drive cycle method and the variable integrallimitingvalue method are proposed. Two methods are realized in real time on the developed digital mass flow transmitter and verified experimentally. The experimental results show that the variable drive cycle method reduces the attenuation degree of the vibration amplitude effectively when the singlephase flow switch to the gasliquid twophase flow, and the variable integrallimitingvalue method solves the significant overshoot of the vibration amplitude well when the gasliquid twophase flow switch to the singlephase flow.