In order to achieve accurate respiratory treatment for patients with mechanical ventilation, it is necessary to monitor the status parameters of the patients" breathing and expiratory bodies in real time. At present, the state parameters of patients" breathing and expiratory bodies are mainly measured by respirators, which have problems such as insufficient parameters, circuit leakage, and are also limited by distance and obstacles. In view of the above problems, this paper designs a wireless sensor and system that can simultaneously monitor the temperature, humidity, carbon dioxide concentration, pressure and flow of breathing gas. It has the characteristics of low power consumption and small size, and can transmit the measured data to the data receiver in real time through the blue tooth for low power wireless transmission, so as to realize the comprehensive monitoring and remote monitoring and evaluation of the respiratory status of patients with mechanical ventilation, Improve the therapeutic effect of medical equipment. At the same time, the sensor does not need external power supply, and can continue to work for about 60 days, covering the entire time of most patients with mechanical ventilation in the ICU and implementing real-time wireless monitoring throughout the whole process.