In the large scale mechanics experiment, we need to acquire a large amount of strain in the key parts of the specimen for providing reliable strength data for the design of the structure and the experimental verification. A data acquisition system based on virtual instrument LabVIEW, adopts “producerconsumer” structure based on the synchronous data acquisition, use queue and notification technology, and realizesthe data acquisition of the hundreds of channels on the large mechanical experiment. It has three kinds of mode strain data acquisition function includingcontinuous acquisition, timing acquisition and single point acquisition, and has the collected data wavedisplay and the processing of the test data, recording, preservation and recall. The multichannel strain acquisition system adopts TDMS format to store, getting tens of thousands of sampling points per second.The experimental results show that the acquisition process is stable, reliable and efficient to meet the needs of the experimentthrough 120 ohm resistance test.It also provides a friendly humanmachine interface. It is easy for system maintenance, upgrade, function expansion, and strong flexibility.