Aiming at the problem of co-channel interference when users reuse spectrum resources in D2D communication, an improved Hunter prey optimization algorithm is proposed to control the power of D2D users. It adjusts the D2D transmission power according to the rules that the hunter moves to the prey and the prey moves to the safest position under the constraints of satisfying the communication quality of the system users. The Sobol sequence initializes the population, and introduces the water wave dynamic adaptive factor into the predator position update formula, so as to determine the optimal transmit power of D2D users. The simulation results show that the algorithm can not only improve the total throughput of the system and reduce the interference to cellular users, but also improve the convergence speed and optimization accuracy.