Aiming at the phenomenon that the wireless signal penetrates the wall under the influence of non-line-of-sight factors in indoor positioning, the positioning is offset. Because the radio signal propagation has the characteristics of strong volatility and easy interference, the use of strong anti-interference, high penetrating power and Ultra-wideband technology with excellent ranging value collects measurement data. In this paper, the signal through-wall derivation formula is combined with the wireless signal logarithmic attenuation model to process the collected distance value data. The attenuation model reduces the energy loss of the signal when passing through the wall, improves the accuracy of the ranging value, and reduces the measurement by the least square method. Accumulated error of distance to improve positioning accuracy. Through the test of actual experimental scenes, it is concluded that the positioning accuracy of this method can reach 0.28m in a through-wall environment, which meets the accuracy requirements and can provide services for general location requirements.