In order to solve the three dimensional block matching algorithm on the processing image edge of high-frequency pseudo like ladder and inhibition effect, this paper proposes a adaptive BM3D algorithm based on generalized variational all. First, after a preliminary classification get two blocks with different structure information subset. In a complex change of subset, considering the adaptive algorithm can significantly reduce the BM3D algorithm used to match the traversal, to adopt adaptive reference block matching the area; In a uniform variation of subset, application of the original fixed reference block size. The staircase effect in view of the image processing, this paper puts forward a new kind of generalized variational (CTGV), second order total generalized variational can automatic balance of first and second order partial derivative of the image features, this paper introduced the variation coefficient, the adjustable generalized variational diffusion effect. By comparison with the experimental data, the algorithm compared with BM3D algorithm and other algorithms, image PSNR improvement more than 1～2 db, SSIM values also have a significant boost, contrast visual effects, this algorithm is effective in addition to the high frequency artifacts and the effect of the inhibition of ladder.