The design of intelligent drug storage box conforms to the trend of social aging. Taking the protection of vulnerable groups and special drug storage as the research object, the intelligent requirements of target monitoring, alarm clock reminder and drug storage are deeply studied. In this paper, an intelligent drug storage box is designed, aiming at the physiological ability degradation of special groups and the demand of special drug storage. Users can stably mobilize the resources of the whole intelligent drug storage box through the human-computer interaction page, including timely medication reminder, opening detection of the drug storage box, temperature control, emergency alarm and other functions. The combination of infrared detection and multi-level signal operational amplifier is adopted in the design process, which can accurately measure the user's heart rate within 5 seconds. The functions set in the intelligent drug storage box can run stably, and the success rate is close to 100%. The results of many experiments show that the design can solve the problem of medication on time for patients and other special groups, at the same time, it is convenient for family members to observe the patient information, and can effectively facilitate the daily life of patients.