Wireless sensor network (WSN) communication channel is designed to balance the inter symbol interference between wireless sensor nodes, and improve the quality of communication. A WSN communication channel equalization algorithm based on direct sequence spread spectrum is proposed. The WSN channel model is designed. In order to reduce the steadystate error of the output of the channel, the time reversal mirror is used as the matched filtering method, and the inter symbol interference filter is designed. The channel equalization of WSN communication is realized by the direct sequence spread spectrum method. Simulation results show that using the algorithm for WSN communication channel equalization design and emission signals along each path arrival signal components of the receiver to get accurate separation, signal multipath components are no bit errors at the receiver, communication channel equalization effect better and reduce the communication bit error rate, to improve the quality of communication of WSN, shows a good application value.