This paper designs a wireless vital signs information monitoring system based on Android and single chip. System with minimum system of microcontroller MSP430F149 as foundation, at the same time, temperature sensor DS18B20 and PulseSensor pulse sensor module to collect information signs and communication through the Android applications people WiFi module USRWIFI232D2 and ANN. After debugging and testing system to achieve the realtime remote sensing of temperature and pulse information, exceeds the threshold alarm function. The system is highly sensitive, high precision, with the characteristics of low power consumption, intuitive and reliable, easy to operate, easy to use etc., has good practical value and broad application prospect.